Status: Planned First registered on: 01/12/2020
Last updated on: 09/12/2020
1. Study identification
EU PAS Register NumberEUPAS38362
Official titleThe risk of musculoskeletal adverse outcomes after treatment with endocrine blocking treatments for breast cancer
Study title acronymMSK_AI
Study typeObservational study
Brief description of the studyTo evaluate the comparative risk of musculoskeletal side effects following treatment with tamoxifen versus aromatase inhibitors
Was this study requested by a regulator?No
Is the study required by a Risk Management Plan (RMP)? Not applicable
Regulatory procedure number (RMP Category 1 and 2 studies only)
Other study registration identification numbers and URLs as applicable
2. Research centres and Investigator details
Coordinating study entity
Centre nameNDORMS
Centre locationUniversity of Oxford
Details of (Primary) lead investigator
Title Miss
Last name Jennifer
First name Lane
Is this study being carried out with the collaboration of a research network?
Yes
OHDSI (EHDEN)
Other centres where this study is being conducted
Multiple centres

In total how many centres are involved in this Study?3

IQVIA
IDIAPJGol, Spain
NDORMS, University of Oxford, UK
Countries in which this study is being conducted
International study

Germany
Spain
United Kingdom
United States
3. Study timelines: initial administrative steps, progress reports and final report
PlannedActual
Date when funding contract was signed02/11/2020
Start date of data collection14/12/2020
Start date of data analysis
Date of interim report, if expected
Date of final study report01/07/2021
4. Sources of funding
Please provide estimates of the percentage of funding by source for this study
Names(s)Approximate % funding
Pharmaceutical companies
CharitiesMRC, NIHR, Versus Arthritis100
Government body
Research councils
EU funding scheme
5. Contact details for enquiries
Scientific Enquiries
Title Miss
Last name Jennifer
First name Lane
Address line 1Botnar research centre
Address line 2NDORMS 
Address line 3Windmill Road 
CityOxford 
PostcodeOX3 7LD 
CountryUnited Kingdom
Phone number (incl. country code)441865223725 
Alternative phone number 
Fax number (incl. country code) 
Email address jennifer.lane@ndorms.ox.ac.uk
Public Enquiries
Title Miss 
Last name Jennifer 
First name Lane 
Address line 1Botnar research centre 
Address line 2NDORMS 
Address line 3Windmill Road 
CityOxford 
PostcodeOX3 7LD 
CountryUnited Kingdom 
Phone number (incl. country code)441865223725 
Alternative phone number 
Fax number (incl. country code) 
Email address jennifer.lane@ndorms.ox.ac.uk 
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