Last updated on: 01/12/2021
Name of organisation
1) Department/Research groupDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging
2) Organisation/affiliationUniversity of Messina
Short Name in the inventoryUniversity of Messina
Administrative Contact
Title Miss
Last name Ientile
First name Valentina
Address line 1Via Consolare Valeria 1
Address line 2
Address line 3
CityMessina
Postcode98125
CountryItaly
Phone number (incl. country code)0039-090-2213877
Alternative phone number
Fax number (incl. country code)0039-0902213300
Scientific Contact
Title Miss
Last name Ientile
First name Valentina
Address line 1Via Consolare Valeria 1
Address line 2
Address line 3
CityMessina
Postcode98125
CountryItaly
Phone number (incl. country code)0039-090-2213877
Alternative phone number
Fax number (incl. country code)0039-0902213300
2. Description
The Centre is responsible for collecting and analyzing spontaneous reports of ADR from all over Sicily since 2003. The database include data from 1996. We collaborate with the National Authority (Agenzia Italiana del Farmaco - AIFA) for signal detection and other national/international initiatives concerning drug safety. The Centre has also expertises in the field of pharmacoepidemiology, drug information and drug utilization; several studies are conducted using prescription data from GPs Electronic Health Records. Overall, about 10 people are actively involved in these topics at different levels.
3. Category
University based
Hospital based
Government based
4. Available resources
In houseVia Contacts/Network
Epidemiologist/Pharmacoepidemiologist
Yes
No
Statistician
No
Yes
Clinician
No
Yes
Clinical Pharmacologist
No
Yes
Pharmacist
Yes
No
5. Therapeutic/disease areas of research in drug safety/risk-benefit performed in the past 5 years
Cardiovascular diseases
Disorders of the central nervous system
Endocrine disorders
Geriatrics
Immunological products and vaccines
Infectious diseases
Liver disease
Malignant disease
Musculoskeletal and joint diseases
Psychiatry
Skin disorders
6. Design of drug safety/risk-benefit studies published in the past 5 years
Cohort Study
Case Control Study
Drug Utilisation
Meta-Analysis
Spontaneous reporting data mining
7. Experience in collecting data directly from individual patients/respondents
Number of Studies
Less than 5
Number of patients/respondents involved in the study(ies)
Between 150 and 1499
8. Access to data collection resources
Capacity to conduct face-to-face interviews
Yes
In a clinic
Yes
In the community
Yes
Electronic data capture systems
Yes
System used:
SPSS, SOS, SQL
Interactive voice response systems
No
Call centre
No
9. Experience in secondary research and meta-analysis
No
10. Work with existing data resources in the past 3 years
Name of data resourceNo. of studies
HSD5
Arianna database10
IPCI5
THIN5
11. Registries established by centre
None
12. Experience in collaboration in a study team
Principal Investigator
Collaborating Investigator
13. Current involvement in research networks
Other networks:
Network nameNationalInternationalLink to webpage
14. Interest in research opportunities which are funded
By charities
By government
By research councils
By EU funding schemes
15. Interest in contract research only if free to publish results
Yes
16. Selected publications of the last 5 calendar years
ReferenceLink to web-publication
Trifirò G, Morabito P, Cavagna L, Ferrajolo C, Pecchioli S, Simonetti M, Bianchini E, Medea G, Cricelli C, Caputi AP, Mazzaglia G. Epidemiology of gout and hyperuricaemia in Italy during the years 2005-2009: a nationwide population-based study. Ann Rheum Dis. 2013 May;72(5):694-700.
Trifirò G, Pariente A, Coloma PM, Kors JA, Polimeni G, Miremont-Salamé G, Catania MA, Salvo F, David A, Moore N, Caputi AP, Sturkenboom M, Molokhia M, Hippisley-Cox J, Acedo CD, van der Lei J, Fourrier-Reglat A; EU-ADR group. Data mining on electronic health record databases for signal detection in pharmacovigilance: which events to monitor? Pharmacoepidemiol Drug Saf. 2009 Dec;18(12):1176-84.
Loiacono C, Sgroi C, Coppolino S, Cannata A, Ferrara R, Arcoraci V, Cananzi P, Savica V, Schuemie M, Caputi AP, Trifirò G. How much are biosimilars used in southern Italy?: a retrospective analysis of epoetin utilization in the local health unit of Messina in the years 2010-2011.
BioDrugs. 2012 Apr 1;26(2):113-20.
Trifirò G, Mokhles MM, Dieleman JP, van Soest EM, Verhamme K, Mazzaglia G, Herings R, de Luise C, Ross D, Brusselle G, Colao A, Haverkamp W, Schade R, van Camp G, Zanettini R, Sturkenboom MC. Risk of cardiac valve regurgitation with dopamine agonist use in Parkinson's disease and hyperprolactinaemia: a multi-country, nested case-control study. Drug Saf. 2012 Feb 1;35(2):159-71
Trifirò G, Gambassi G, Sen EF, Caputi AP, Bagnardi V, Brea J, Sturkenboom MC. Association of community-acquired pneumonia with antipsychotic drug use in elderly patients: a nested case-control study. Ann Intern Med. 2010 Apr 6;152(7):418-25.
