Name of organisation
1) Department/Research groupDrug Safety Research Unit
2) Organisation/affiliationDrug Safety Research Unit
Short Name in the inventoryDSRU
Administrative Contact
Title Dr
Last name Lynn
First name Elizabeth
Address line 1DSRU
Address line 2Bursledon Hall
Address line 3Blundell Lane
CitySouthampton
PostcodeSO31 1AA
CountryUnited Kingdom (Northern Ireland)
Phone number (incl. country code)44-2380-408600
Alternative phone number
Fax number (incl. country code)44-2380-408609
Scientific Contact
Title Professor
Last name Shakir
First name Saad
Address line 1DSRU
Address line 2Bursledon Hall
Address line 3Blundell Lane
CitySouthampton
PostcodeSO31 1AA
CountryUnited Kingdom (Northern Ireland)
Phone number (incl. country code)44-2380-408600
Alternative phone number
Fax number (incl. country code)United Kingdom
Alternative Scientific Contact
Title Dr
Last name Elizabeth
First name Lynn
Address line 1DSRU
Address line 2Bursledon Hall
Address line 3Blundell Lane
CitySouthampton
PostcodeSO31 1AA
Country
Phone number (incl. country code)442380408600
Alternative phone number
Fax number (incl. country code)
2. Description
The Drug Safety Research Unit (DSRU) is the UK’s premier pharmacovigilance and pharmacoepidemiology unit. As an independent academic research organisation, the DSRU is internationally renowned for its work in drug safety, risk management, risk minimisation and training services for 40 years. The Unit aims to protect patients from unwanted adverse effects of medicines in clinical use. The DSRU has grown into a broad pharmacoepidemiological unit which uses a variety of methods to conduct a wide range of studies, including Post Authorisation Safety Studies (PASS) in primary and secondary care, CPRD studies, drug utilisation studies, registries, risk minimisation studies, benefit-risk assessments, systematic reviews and much more.
The DSRU has a highly experienced research team, which includes medics, epidemiologists and biomedical scientists, supported by IT and data management staff.
3. Category
Charity or non-profit organisation
4. Available resources
In houseVia Contacts/Network
Epidemiologist/Pharmacoepidemiologist
Yes
No
Statistician
No
Yes
Clinician
Yes
No
Clinical Pharmacologist
No
Yes
Pharmacist
No
Yes
IT specialist
Yes
No
Ethics expertise
Yes
No
Legal expertise
No
Yes
Regulatory expertise
No
Yes
5. Therapeutic/disease areas of research in drug safety/risk-benefit performed in the past 5 years
Cardiovascular diseases
Endocrine disorders
Gastrointestinal tract
Immunological products and vaccines
Musculoskeletal and joint diseases
Nutrition and blood
Osteoporosis
Pregnancy
Psychiatry
Respiratory diseases
Skin disorders
Urinary tract disorders
6. Design of drug safety/risk-benefit studies published in the past 5 years
Cohort Study
Case Control Study
Drug Utilisation
Meta-Analysis
7. Experience in collecting data directly from individual patients/respondents
Number of Studies
Greater than 5
Number of patients/respondents involved in the study(ies)
Greater than 15000
8. Access to data collection resources
Capacity to conduct face-to-face interviews
Yes
In a clinic
No
In the community
Yes
Electronic data capture systems
Yes
System used:
Bespoke in-house system
Interactive voice response systems
No
Call centre
Yes
9. Experience in secondary research and meta-analysis
Yes
10. Work with existing data resources in the past 3 years
Name of data resourceNo. of studies
CPRD10
11. Registries established by centre
Drug RegistryRivaroxaban, seroquel XR, asenapine
Disease RegistryDrug-induced arrhythmias
12. Experience in collaboration in a study team
Principal Investigator
Collaborating Investigator
13. Current involvement in research networks
Networks registered with ENCePP
VAC4EU